Description

n-(7-Nitro-4-Benzofurazanyl)-D-Prolyl is a specialized chiral compound featuring a benzofurazan (benzofuroxan) fluorophore coupled with a D-proline moiety. This unique structure makes it a valuable intermediate and research chemical, particularly in the development of analytical probes and advanced pharmaceutical building blocks. It is primarily sought by research institutions and fine chemical manufacturers engaged in chiral synthesis, fluorescence labeling, and the study of enzyme-substrate interactions.

Application

• Fluorescent Probe Development: Serves as a key precursor for synthesizing advanced fluorescent tags and sensors used in biochemical assays and cellular imaging.
• Chiral Intermediate: Utilized in the asymmetric synthesis of complex molecules, leveraging its D-proline configuration for inducing stereoselectivity.
• Pharmaceutical Research: Acts as a building block in the discovery and development of new active pharmaceutical ingredients (APIs), especially those targeting proteases or requiring specific chiral centers.
• Bioconjugation Chemistry: The reactive benzofurazanyl group can be used for labeling peptides, proteins, and other biomolecules for diagnostic or research purposes.
• Material Science Research: Investigated for potential use in creating novel organic electronic materials or photoresponsive polymers.

Basic Information

Product Name	n-(7-Nitro-4-Benzofurazanyl)-D-Prolyl
CAS No.	159717-69-8
Molecular Formula	C₁₃H₁₂N₄O₅
Molecular Weight	304.26 g/mol
Synonyms	D-Proline, N-(7-nitro-4-benzofurazanyl)-; 7-Nitro-N-(D-prolyl)-4-benzofurazanamine; N-(7-Nitro-4-benzofurazanyl)-D-proline amide; 4-(7-Nitro-4-benzofurazanyl)-D-proline; NBDF-Prolyl; 7-Nitro-4-benzofurazan-D-prolyl derivative; (R)-1-(7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)pyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our n-(7-Nitro-4-Benzofurazanyl)-D-Prolyl is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.