Description

2-(4-Isothiocyanatophenoxy)Ethyl Tosylat is a specialized bifunctional organic intermediate featuring both a reactive isothiocyanate group and a tosylate leaving group. This unique structure makes it a valuable building block for the synthesis of complex molecules, particularly in the development of targeted pharmaceuticals and advanced materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology sectors for creating novel conjugates and probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted drug conjugates, antibody-drug conjugates (ADCs), and small molecule therapeutics.
• Bioconjugation Reagent: Used for labeling proteins, peptides, and antibodies via reaction with amine groups, enabling the creation of diagnostic probes and research tools.
• Material Science: Serves as a cross-linking agent or functional monomer in the development of specialty polymers and functionalized surfaces.
• Agrochemical Research: Intermediate in the design and synthesis of novel active ingredients with specific biological activity.
• Chemical Biology Probes: Facilitates the development of activity-based probes (ABPs) for studying enzyme function and metabolic pathways.
• Ligand Synthesis: Building block for creating chelating agents and ligands used in catalysis or metal ion sequestration.

Basic Information

Product Name	2-(4-Isothiocyanatophenoxy)Ethyl Tosylat
CAS No.	155863-33-5
Molecular Formula	C16H15NO4S2
Molecular Weight	349.42 g/mol
Synonyms	2-[4-(Isothiocyanato)phenoxy]ethyl 4-methylbenzenesulfonate; 4-Methylbenzenesulfonic Acid 2-[4-(Isothiocyanato)phenoxy]ethyl Ester; 2-(4-Isothiocyanatophenoxy)Ethyl p-Toluenesulfonate; p-Toluenesulfonic Acid 2-(4-Isothiocyanatophenoxy)ethyl Ester; Tosyloxyethyl Isothiocyanatophenoxy Ether; Bifunctional Isothiocyanate-Tosylate Linker
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Isothiocyanatophenoxy)Ethyl Tosylat is manufactured and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.