Description

6-Fluoro L-Dopa Hydrobromide Salt is a fluorinated derivative of the important neurotransmitter precursor L-DOPA, modified with a hydrobromide salt for enhanced stability and handling. This compound serves as a critical intermediate in the research and development of novel pharmaceuticals, particularly for neurological applications. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing advanced therapeutic agents for conditions like Parkinson's disease.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluorinated dopaminergic agents and other central nervous system (CNS) active compounds.
• Neurological Research: Used in preclinical studies to investigate the structure-activity relationships (SAR) of dopamine analogs and their transport mechanisms.
• PET Tracer Development: Serves as a precursor in the research and synthesis of potential positron emission tomography (PET) radiotracers for imaging dopaminergic pathways.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: A valuable scaffold for chemical modification in drug discovery programs targeting neurodegenerative diseases.
• Biochemical Studies: Utilized in enzymatic and receptor-binding assays to study the effects of fluorination on biological activity.

Basic Information

Product Name	6-Fluoro L-Dopa Hydrobromide Salt
CAS No.	154051-94-2
Molecular Formula	C9H11BrFNO4
Molecular Weight	296.09 g/mol
Synonyms	(2S)-2-Amino-3-(2-fluoro-4,5-dihydroxyphenyl)propanoic acid hydrobromide; 6-Fluoro-L-3,4-dihydroxyphenylalanine HBr; 6-F-DOPA HBr; 6-Fluoro-L-DOPA hydrobromide; L-6-Fluorodopa HBr; (S)-2-Amino-3-(2-fluoro-4,5-dihydroxyphenyl)propanoic acid hydrobromide; 6-Fluoro-levodopa hydrobromide
EINECS	Contact for details

Quality Control

Our 6-Fluoro L-Dopa Hydrobromide Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.