Description

2,4-Difluoro-5-Nitrobenzoic Acid is a versatile aromatic building block characterized by its strategically positioned fluorine and nitro substituents. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique substitution pattern enables the introduction of key functional groups. It is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing a difluorobenzene core.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the nitro and fluorine groups.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and reduction reactions to create more complex molecular architectures.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the nitro group acts as an auxochrome.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	2,4-Difluoro-5-Nitrobenzoic Acid
CAS No.	153775-33-8
Molecular Formula	C7H3F2NO4
Molecular Weight	203.10 g/mol
Synonyms	5-Nitro-2,4-difluorobenzoic Acid; 2,4-Difluoro-5-nitrobenzoic acid; Benzoic acid, 2,4-difluoro-5-nitro-; 153775-33-8; 2,4-Difluoro-5-nitro-benzoic acid; 5-Nitro-2,4-difluorobenzoicacid; AKOS005258155; SCHEMBL1550559
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-5-Nitrobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your application. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.