Description

4-Bromo-3-Fluorobenzoic Acid is a high-purity halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of halogenated aromatics.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce halogenated aromatic units into polymer chains, enhancing material properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	4-Bromo-3-Fluorobenzoic Acid
CAS No.	153556-42-4
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	3-Fluoro-4-bromobenzoic Acid; Benzoic acid, 4-bromo-3-fluoro-; 4-Bromo-3-fluorobenzoic acid; 153556-42-4; 3-Fluoro-4-bromobenzoic acid; 4-Bromo-3-fluoro-benzoic acid; 4-Br-3-F-BA
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, guaranteeing the product meets your specified requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.