Description

Ethyl 3,5-Difluoro-2-Pivalamido-6-((Tetrahydro-2H-Pyran-2-Yl)Oxy)-4-(Trimethylsilyl)Benzoate is a sophisticated, multi-functional organic intermediate featuring a unique combination of fluorine, silyl, and protected hydroxyl groups. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures where precise steric and electronic control is required. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially in fluorinated compound libraries.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that benefit from the stability and lipophilicity imparted by its functional groups.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in catalyst systems due to the presence of the trimethylsilyl and THP-protected oxygen.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or probes for studying biological mechanisms, leveraging its fluorine atoms for potential 19F NMR applications.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex target molecules in fine chemical manufacturing.

Basic Information

Product Name	Ethyl 3,5-Difluoro-2-Pivalamido-6-((Tetrahydro-2H-Pyran-2-Yl)Oxy)-4-(Trimethylsilyl)Benzoate
CAS No.	152835-84-2
Molecular Formula	C22H33F2NO5Si
Molecular Weight	469.59 g/mol
Synonyms	Ethyl 4-(Trimethylsilyl)-3,5-difluoro-2-pivalamido-6-(tetrahydro-2H-pyran-2-yloxy)benzoate; Benzoic acid, 3,5-difluoro-2-[(2,2-dimethyl-1-oxopropyl)amino]-6-(tetrahydro-2H-pyran-2-yloxy)-4-(trimethylsilyl)-, ethyl ester; 152835-84-2; 3,5-Difluoro-2-pivalamido-6-(tetrahydro-2H-pyran-2-yloxy)-4-(trimethylsilyl)benzoic Acid Ethyl Ester; Ethyl 3,5-Difluoro-2-(pivalamido)-6-((tetrahydro-2H-pyran-2-yl)oxy)-4-(trimethylsilyl)benzoate
EINECS	Contact for details

Quality Control

Our production of Ethyl 3,5-Difluoro-2-Pivalamido-6-((Tetrahydro-2H-Pyran-2-Yl)Oxy)-4-(Trimethylsilyl)Benzoate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.