Description

Bstfa-Tmcs CAS NO 152571-61-4 is a specialized derivatization reagent, a mixture of N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA) and Trimethylchlorosilane (TMCS). This combination is critical for enhancing the volatility and thermal stability of polar compounds for precise analytical detection. It is an essential tool for analytical chemists and quality control laboratories requiring accurate compound identification and quantification. Its primary value lies in enabling reliable gas chromatographic analysis of complex samples across demanding industries.

Application

• Gas Chromatography (GC) and GC-MS Sample Preparation: As a premier silylation agent for derivatizing hydroxyl, carboxyl, and amine groups in organic compounds to improve their chromatographic behavior.
• Pharmaceutical Analysis: Used in the analysis of drug metabolites, steroids, and other active pharmaceutical ingredients (APIs) that require derivatization for detection.
• Environmental Testing: Employed for the derivatization and subsequent analysis of pollutants, pesticides, and phenolic compounds in water and soil samples.
• Forensic Toxicology: Essential for preparing biological samples (e.g., blood, urine) for the detection of drugs of abuse and toxins.
• Food and Flavor Chemistry: Facilitates the analysis of sugars, organic acids, and flavor compounds that are not directly amenable to GC.
• Petrochemical and Fuel Analysis: Used to silylate oxygenated species and other polar components in complex hydrocarbon mixtures for detailed characterization.
• Biochemical Research: Aids in the analysis of amino acids, fatty acids, and other metabolites in proteomic and metabolomic studies.

Basic Information

Product Name	Bstfa-Tmcs
CAS No.	152571-61-4
Molecular Formula	C8H18F3NOSi2 • C3H9ClSi (Mixture)
Molecular Weight	Contact for details
Synonyms	BSTFA with TMCS; BSTFA:TMCS; N,O-Bis(trimethylsilyl)trifluoroacetamide with 1% Trimethylchlorosilane; Silylation Mixture BSTFA/TMCS; Derivatization Reagent BSTFA+TMCS; TMS Reagent with Catalyst; Trimethylsilylating Mixture
EINECS	Contact for details

Quality Control

Our Bstfa-Tmcs is manufactured under strict quality-controlled conditions to ensure high reactivity and consistency for sensitive analytical applications. Each batch is tested to confirm its derivatization efficacy and purity profile. A comprehensive Certificate of Analysis (COA) is provided, detailing key parameters such as assay, identity, and clarity. We adhere to relevant industry standards to support our customers' compliance needs in pharmaceutical, environmental, and research laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation by atmospheric moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Assay (BSTFA)	≥ 99.0% (by GC)
Assay (TMCS)	1.0 ± 0.2% (by GC)
Water Content (KF)	≤ 0.1%
Clarity	Clear, free from suspended matter

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.