Description

Methyl 4-Fluoro-2-Nitrobenzoate is a high-purity fluorinated aromatic ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the fluorine and nitro groups on the benzoate ring, enabling precise functionalization for complex molecule construction. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom improves lipophilicity and biological activity.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated organic electronic materials and liquid crystal compounds.
• Dye & Pigment Intermediate: Employed in the production of specialized fluorinated dyes and pigments with unique color fastness and optical properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing biaryl systems.
• Nitro Group Reduction: The nitro group can be selectively reduced to an amine, providing access to a versatile aniline derivative for further functionalization.

Basic Information

Product Name	Methyl 4-Fluoro-2-Nitrobenzoate
CAS No.	151504-81-3
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	4-Fluoro-2-nitrobenzoic acid methyl ester; Methyl 4-fluoro-2-nitrobenzoate; Benzoic acid, 4-fluoro-2-nitro-, methyl ester; 2-Nitro-4-fluorobenzoic acid methyl ester; Methyl 2-nitro-4-fluorobenzoate; 4-Fluoro-2-nitro methyl benzoate; 151504-81-3; MFCD03094045
EINECS	Contact for details

Quality Control

Our Methyl 4-Fluoro-2-Nitrobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.