Description

2-Chloro-3,4-Difluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen and fluorine substituents, which are essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the development of new herbicides and pharmaceutical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a core precursor in the development of next-generation herbicides and pesticides, where the difluoro and chloro groups enhance biological activity and environmental stability.
• Liquid Crystal Material Precursor: Used in the synthesis of fluorinated liquid crystal compounds for advanced display technologies.
• Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polymers, including high-performance engineering plastics and coatings with improved chemical resistance.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex aromatic systems.
• Material Science Research: Utilized in academic and industrial R&D for creating novel organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Chloro-3,4-Difluorobenzoic Acid
CAS No.	150444-93-2
Molecular Formula	C7H3ClF2O2
Molecular Weight	192.55 g/mol
Synonyms	3,4-Difluoro-2-chlorobenzoic Acid; Benzoic acid, 2-chloro-3,4-difluoro-; 2-Chloro-3,4-difluorobenzoic acid; 150444-93-2; 3,4-Difluoro-2-chloro-benzoic acid; 2-Chloro-3,4-difluoro-benzoic acid; NSC 405124; A1-00832
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3,4-Difluorobenzoic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.