Description

10,11-Dihydroxy-n-(n-2-Fluoroethyl)Norapomorphine is a specialized fluorinated derivative of the aporphine alkaloid class, designed for advanced research and development. This compound is of significant interest due to its potential as a high-affinity ligand for studying dopaminergic receptor systems in neurological research. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and contract research organizations (CROs) focused on neuroscience, neuropharmacology, and the development of novel central nervous system (CNS) therapeutics.

Application

• Neuroscience Research: Acts as a key biochemical tool for investigating dopamine receptor (particularly D1 and D2) pharmacology, signaling pathways, and function.
• Neuropharmacology Studies: Used in in vitro and in vivo models to study the effects of dopaminergic modulation, potentially relevant to conditions like Parkinson's disease.
• Radiopharmaceutical Precursor: Serves as a precursor or reference standard in the development of fluorine-18 (18F) labeled tracers for Positron Emission Tomography (PET) imaging of the brain.
• Medicinal Chemistry: Provides a structurally complex scaffold for the design and synthesis of new chemical entities targeting G-protein coupled receptors (GPCRs).
• Reference Standard: Used as an analytical standard in method development and quality control for related pharmaceutical compounds and impurities.

Basic Information

Product Name	10,11-Dihydroxy-n-(n-2-Fluoroethyl)Norapomorphine
CAS No.	149156-25-2
Molecular Formula	C18H20FNO3
Molecular Weight	317.36 g/mol
Synonyms	N-(2-Fluoroethyl)norapomorphine-10,11-diol; 10,11-Dihydroxy-N-(2-fluoroethyl)norapomorphine; 2-Fluoroethylnorapomorphine-10,11-diol; (R)-10,11-Dihydroxy-N-(2-fluoroethyl)noraporphine; Norapomorphine, 10,11-dihydroxy-N-(2-fluoroethyl)-; FENAP; Aporphine derivative, fluorinated
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results from HPLC, NMR, and mass spectrometry are available upon request. We support research integrity with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This compound is hygroscopic (moisture-sensitive); the container must be kept in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light brown solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.