Description

Trecovirsen is a synthetic phosphorothioate oligonucleotide designed as an antiviral agent. This compound is of significant interest in pharmaceutical research and development due to its targeted mechanism of action against viral infections. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel antiviral therapeutics, particularly for conditions such as cytomegalovirus (CMV) retinitis. Trecovirsen CAS NO 148998-94-1 represents a critical building block in advanced medicinal chemistry.

Application

• Antiviral Drug Research: Serves as a key active pharmaceutical ingredient (API) or intermediate in the development of treatments for viral infections.
• Biochemical Research: Used as a tool compound in virology and molecular biology studies to investigate oligonucleotide-based therapeutic mechanisms.
• Pharmaceutical Development: Employed in pre-clinical and formulation studies for antiviral medications.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	Trecovirsen
CAS No.	148998-94-1
Molecular Formula	C204H247N63O114P19S19
Molecular Weight	Approx. 6260.8 g/mol
Synonyms	GEM 91; ISIS 2922; Trecovirsen sodium; 5'-d(GmCmGmTmTmTmCmTmCmTmCmGm)-3'; Phosphorothioate oligonucleotide GEM91; Anti-CMV oligonucleotide; Novivir
EINECS	Contact for details

Quality Control

Our Trecovirsen is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under desiccant to maintain stability and prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (UV)	90.0% - 110.0% of labeled amount
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.