Description

Bexlosteride is a potent and selective nonsteroidal inhibitor of the enzyme 5α-reductase type 2. This compound is of significant interest in pharmaceutical research and development for its role in modulating androgen-dependent pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutics for conditions such as benign prostatic hyperplasia (BPH), androgenetic alopecia, and other hormone-related disorders. Bexlosteride. CAS NO 148905-78-6.

Application

• Pharmaceutical R&D Intermediate: Serves as a key chemical entity in the research and synthesis of novel 5α-reductase inhibitors.
• Biochemical Research: Used as a selective tool compound in enzymatic assays and studies to understand androgen metabolism and signaling pathways.
• Preclinical Studies: Employed in animal models to investigate efficacy and pharmacokinetics for potential treatments of prostate-related conditions.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Mechanistic Studies: Utilized to explore the differential roles of 5α-reductase isozymes in physiology and disease states.

Basic Information

Product Name	Bexlosteride
CAS No.	148905-78-6
Molecular Formula	C₂₃H₂₆N₂O₂
Molecular Weight	362.47 g/mol
Synonyms	4-Methyl-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide; BXL-628; 1,2-Dihydro-4-methyl-2-(4-morpholinyl)-6-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)-1-(2-propynyl)-5H-pyrrolo[3,2-d]pyrimidin-5-one; UNII-8JQ5607E5S
EINECS	Contact for details

Quality Control

Our Bexlosteride is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.