Description

Benzoic Acid, 2-(2,2,2-Trifluoro-1-Hydroxyethyl)- (9Ci) is a fluorinated benzoic acid derivative characterized by a trifluoroethanol side chain, offering unique physicochemical properties for advanced synthesis. This compound is valued for its role as a key chiral intermediate and building block in the development of high-value, complex molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for developing novel fluorinated polymers with specific thermal or chemical resistance properties.
• Organic Synthesis Reference Standard: Employed as a high-purity standard in analytical laboratories for method development and quality control.

Basic Information

Product Name	Benzoic Acid, 2-(2,2,2-Trifluoro-1-Hydroxyethyl)- (9Ci)
CAS No.	148527-65-5
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	2-(2,2,2-Trifluoro-1-hydroxyethyl)benzoic acid; α-(Trifluoromethyl)mandelic acid; 2-[1-Hydroxy-2,2,2-trifluoroethyl]benzoic acid; (2-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)formic acid; Benzoic acid, 2-(2,2,2-trifluoro-1-hydroxyethyl)-; 2-(1-Hydroxy-2,2,2-trifluoroethyl)benzoic acid; TFMA (context-dependent abbreviation)
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-(2,2,2-Trifluoro-1-Hydroxyethyl)- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.