Description

7-Aminosulfonyl-4-(2,1,3-Benzoxadiazolyl)Isothiocyanate is a specialized heterocyclic organic compound that serves as a critical derivatization reagent and synthetic intermediate. Its core value lies in its reactive isothiocyanate group, which enables efficient conjugation with amines and other nucleophiles for labeling and analytical applications. This compound is primarily needed by research institutions and industrial laboratories in the fields of analytical chemistry, pharmaceutical development, and life sciences for creating fluorescent probes and advanced molecular conjugates.

Application

• Derivatization Reagent for HPLC Analysis: Used for the pre-column or post-column derivatization of amines, amino acids, and peptides to enhance their detection sensitivity via fluorescence or UV.
• Fluorescent Labeling Agent: Acts as a key building block for synthesizing fluorescent dyes and probes for bioimaging, cellular staining, and diagnostic assays.
• Pharmaceutical Intermediate: Employed in the research and development of novel drug candidates, particularly those targeting specific enzymes or receptors.
• Bioconjugation Chemistry: Facilitates the covalent attachment of reporter molecules, drugs, or other functional groups to proteins, antibodies, or nanoparticles.
• Material Science Research: Used in the synthesis of advanced organic materials with specific optical or electronic properties.
• Chemical Biology Tools: Integral for creating activity-based probes (ABPs) to study enzyme function and mechanism in complex biological systems.

Basic Information

Product Name	7-Aminosulfonyl-4-(2,1,3-Benzoxadiazolyl)Isothiocyanate
CAS No.	147611-82-3
Molecular Formula	C7H4N4O3S2
Molecular Weight	256.26 g/mol
Synonyms	4-(2,1,3-Benzoxadiazol-4-yl)-7-isothiocyanato-1,2,3-benzoxadiazole; 7-Isothiocyanato-4-(benzo[c][1,2,5]oxadiazol-4-yl)-2,1,3-benzoxadiazole; ABD-F; 4-(2,1,3-Benzoxadiazol-4-yl)-7-isothiocyanato-2,1,3-benzoxadiazole; 7-Aminosulfonyl-4-(benzo[1,2,5]oxadiazolyl)isothiocyanate; 4-(7-Isothiocyanato-2,1,3-benzoxadiazol-4-yl)-2,1,3-benzoxadiazole
EINECS	Contact for details

Quality Control

Our 7-Aminosulfonyl-4-(2,1,3-Benzoxadiazolyl)Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.