Description

Methyl 2-Amino-6-(Trifluoromethyl)Benzoate is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its structure, featuring both an amino and a trifluoromethyl group on the benzoate core, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic materials for displays and lighting.
• Functional Dye & Pigment Intermediate: Serves in the creation of specialized dyes with unique colorfastness and optical properties.
• Organic Synthesis Reagent: A versatile starting material for amide coupling, cyclization, and further functionalization reactions in complex molecule assembly.
• Chemical Research & Development: Utilized in academic and industrial labs for exploring new fluorination methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	Methyl 2-Amino-6-(Trifluoromethyl)Benzoate
CAS No.	147494-56-2
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	2-Amino-6-(trifluoromethyl)benzoic acid methyl ester; Methyl 2-amino-α,α,α-trifluoro-o-toluate; Benzoic acid, 2-amino-6-(trifluoromethyl)-, methyl ester; Methyl 2-amino-6-trifluoromethylbenzoate; 2-(Trifluoromethyl)anthranilic acid methyl ester; Methyl α,α,α-trifluoro-2-aminobenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Amino-6-(Trifluoromethyl)Benzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed to minimize exposure to atmospheric moisture and light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.