Description

5-Fluoro-1-Benzofuran-3-Carboxylic Acid is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for its unique structural and electronic properties imparted by the fluorine substituent.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, potentially targeting a range of therapeutic areas.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the benzofuran scaffold and fluorine atom can enhance bioactivity and environmental stability.
• Material Science: Serves as a monomer or precursor for specialty polymers, liquid crystals, and organic electronic materials due to its rigid, planar structure.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, enzyme inhibitors, and fluorescent tags.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploratory synthesis of novel heterocyclic compounds.
• Fine Chemical Synthesis: Acts as a versatile intermediate for creating more complex fluorinated organic molecules for various specialty chemical applications.

Basic Information

Product Name	5-Fluoro-1-Benzofuran-3-Carboxylic Acid
CAS No.	147373-09-9
Molecular Formula	C9H5FO3
Molecular Weight	180.13 g/mol
Synonyms	5-Fluorobenzofuran-3-carboxylic acid; 5-Fluoro-3-benzofurancarboxylic acid; 5-Fluoro-1-benzofuran-3-carboxylic acid; 5-Fluoro-benzo[b]furan-3-carboxylic acid; 147373-09-9; 5-Fluorobenzofurane-3-carboxylic acid; 5-F-BFC Acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-Benzofuran-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.