Description

2-(1-Pyrenyl)Ethyl Chloroformate is a specialized derivatization reagent designed for the selective labeling and analysis of complex molecules. This compound matters for its role in enhancing detection sensitivity and selectivity in advanced analytical techniques, particularly for compounds containing amine or hydroxyl functional groups. It is primarily needed by research and development laboratories in the pharmaceutical, biotechnology, and analytical chemistry sectors for method development and high-sensitivity trace analysis.

Application

• HPLC and LC-MS Derivatization Agent: Used to tag amines, amino acids, and other analytes to improve chromatographic separation and mass spectrometric detection.
• Fluorescent Labeling Reagent: The pyrenyl moiety provides a strong fluorescent signal for sensitive detection in fluorescence-based assays and detection systems.
• Proteomics and Metabolomics Research: Facilitates the analysis of low-abundance proteins, peptides, and metabolites by introducing a hydrophobic, fluorescent tag.
• Pharmaceutical Impurity Profiling: Employed in the derivatization of drug substances and related compounds for precise identification and quantification of impurities.
• Biomarker Discovery: Aids in the sensitive detection and quantification of potential biomarkers in biological samples.
• Chemical Synthesis Intermediate: Serves as a building block for synthesizing more complex pyrene-containing compounds for material science or sensor development.

Basic Information

Product Name	2-(1-Pyrenyl)Ethyl Chloroformate
CAS No.	147357-96-8
Molecular Formula	C19H13ClO2
Molecular Weight	308.76 g/mol
Synonyms	1-Pyreneethyl Chloroformate; 2-(1-Pyrenyl)ethyl Chloroformate; 2-(Pyren-1-yl)ethyl Chloroformate; 1-Pyreneethanol Chloroformate; Pyrene-1-ethyl Chloroformate; (1-Pyren-1-ylethyl) Chloroformate; Pyren-1-ylethyl Chloroformate; PECF
EINECS	Contact for details

Quality Control

Our 2-(1-Pyrenyl)Ethyl Chloroformate is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive analytical applications. Each lot undergoes rigorous testing including identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a recommended temperature of 2-8°C. Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.