Description

Octadecanedioic Acid, 1-(2,5-Dioxo-1-Pyrrolidinyl) Ester is a high-purity, functionalized long-chain diacid derivative designed for advanced polymer synthesis and specialty chemical manufacturing. This compound serves as a critical building block, introducing reactive succinimide ester groups and extended aliphatic chains to modify material properties such as crystallinity, hydrophobicity, and cross-linking density. It is essential for R&D chemists and production engineers in the pharmaceutical intermediates, performance polymers, and advanced material coating sectors seeking to develop products with tailored thermal and mechanical characteristics.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, where its long hydrophobic chain and reactive ester group facilitate conjugation and controlled release.
• Polymer Modification & Cross-linking: Acts as a difunctional monomer or cross-linking agent in polyamides, polyesters, and polyurethanes to enhance thermal stability, flexibility, and chemical resistance.
• Specialty Coatings and Adhesives: Incorporated into resin formulations to improve adhesion, durability, and water repellency in high-performance industrial coatings.
• Lubricant and Fuel Additives: Serves as a precursor for synthesizing polymeric dispersants and viscosity modifiers that improve the performance of engine oils and industrial lubricants.
• Bioconjugation and Linker Chemistry: Utilized in biochemical research for labeling proteins, peptides, and other biomolecules due to its reactive N-hydroxysuccinimide (NHS) ester moiety.
• Advanced Material Research: Employed in developing novel dendritic polymers, supramolecular assemblies, and self-healing materials for cutting-edge technological applications.

Basic Information

Product Name	Octadecanedioic Acid, 1-(2,5-Dioxo-1-Pyrrolidinyl) Ester
CAS No.	146004-84-4
Molecular Formula	C24H41NO5
Molecular Weight	423.59 g/mol
Synonyms	1,18-Octadecanedioic Acid 1-(2,5-Dioxo-1-pyrrolidinyl) Ester; Octadecanedioic Acid Mono(N-succinimidyl) Ester; N-Succinimidyl Octadecanedioate Monoester; Succinimidyl Mono-octadecanedioate; 1-(N-Succinimidyloxycarbonyl)heptadecanecarboxylic Acid; NHS-Activated C18 Diacid; C18-Diacid NHS Ester; 18-(2,5-Dioxopyrrolidin-1-yl)oxy-18-oxooctadecanoic Acid
EINECS	Contact for details

Quality Control

Our Octadecanedioic Acid, 1-(2,5-Dioxo-1-Pyrrolidinyl) Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and titration for active ester content, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	95.0 - 105.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.