Description

Ethyl 2-Amino-3-Fluorobenzoate is a high-purity fluorinated benzoate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and ester functionalities into target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated aromatic components in electronic and display materials.
• Organic Synthesis Reagent: Employed in coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a starting material for heterocyclic compounds like benzimidazoles and quinazolines.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new fluorination strategies and structure-activity relationships (SAR).
• Dye & Pigment Intermediate: Serves in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	Ethyl 2-Amino-3-Fluorobenzoate
CAS No.	144851-84-3
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	2-Amino-3-fluorobenzoic Acid Ethyl Ester; Ethyl 2-Amino-3-fluorobenzoate; Benzoic acid, 2-amino-3-fluoro-, ethyl ester; 3-Fluoroanthranilic Acid Ethyl Ester; Ethyl 3-Fluoroanthranilate; 144851-84-3; Ethyl o-amino-m-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-3-Fluorobenzoate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.