Description

Methyl2-Amino-3-Fluorobenzoate CAS NO 144851-82-1 is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its value lies in the strategic combination of the amino and fluoro substituents on the benzoate core, enabling precise molecular modifications. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and pesticides where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials due to its influence on molecular polarity and packing.
• Complex Ligand & Catalyst Development: The amino group allows for functionalization to create specialized ligands for catalytic systems.
• Fluorine-Containing Dye & Pigment Intermediate: Imparts unique photochemical properties in the development of specialty dyes.
• Academic & Contract Research: A valuable reagent for methodological studies in fluorination chemistry and cross-coupling reactions.

Basic Information

Product Name	Methyl 2-Amino-3-Fluorobenzoate
CAS No.	144851-82-1
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	2-Amino-3-fluorobenzoic acid methyl ester; Methyl 3-fluoroanthranilate; 3-Fluoroanthranilic acid methyl ester; Benzoic acid, 2-amino-3-fluoro-, methyl ester; Methyl 2-amino-3-fluorobenzoate; 144851-82-1; Methyl 3-fluoro-2-aminobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-3-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.