Description

4-Benzyloxy-2,3-Difluorobenzoic acid is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in its unique molecular structure, which incorporates both fluorine atoms and a benzyloxy group, enabling precise modifications to enhance the biological activity and pharmacokinetic properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, where the fluorine atoms contribute to improved metabolic stability and efficacy.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Acts as a starting material for synthesizing specialized monomers and polymers used in organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A versatile synthon for introducing the 2,3-difluoro-4-benzyloxybenzoic acid moiety into more complex molecular architectures in medicinal and materials chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific compounds and proprietary development pipelines.

Basic Information

Product Name	4-Benzyloxy-2,3-Difluorobenzoic acid
CAS No.	144292-54-6
Molecular Formula	C14H10F2O3
Molecular Weight	264.22 g/mol
Synonyms	2,3-Difluoro-4-(phenylmethoxy)benzoic Acid; Benzoic acid, 2,3-difluoro-4-(phenylmethoxy)-; 4-(Benzyloxy)-2,3-difluorobenzoic Acid; 2,3-Difluoro-4-benzyloxybenzoic acid; 4-(Phenylmethoxy)-2,3-difluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-2,3-Difluorobenzoic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures batch-to-batch consistency and reliability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.