Description

Eltoprazine Dihydrochloride CAS NO 143485-51-2 is a high-purity, pharmaceutically relevant compound belonging to the class of phenylpiperazine derivatives. This compound is of significant interest for its role as a key intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in neuropharmacology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in drug substance and product testing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents targeting serotonin receptors.
• Preclinical Research & Development: Employed in in vitro and in vivo studies to investigate pharmacological profiles, mechanism of action, and efficacy.
• Metabolite Synthesis: Used as a starting material for the preparation of drug metabolites required for pharmacokinetic and toxicology studies.
• Biochemical Assay Development: Acts as a ligand or inhibitor in high-throughput screening (HTS) assays to identify new drug candidates.
• Academic Research: Supports fundamental neuroscience and medicinal chemistry research in university and institutional laboratories.

Basic Information

Item	Detail
Product Name	Eltoprazine Dihydrochloride
CAS No.	143485-51-2
Molecular Formula	C₁₃H₂₂Cl₂N₄O
Molecular Weight	321.25 g/mol
Synonyms	Eltoprazine HCl; DU 28853; 1-(2,3-Dihydro-1,4-benzodioxin-6-yl)piperazine dihydrochloride; 6-(1-Piperazinyl)-1,4-benzodioxan dihydrochloride; FG-5938; DU-28853; Eltoprazine 2HCl
EINECS	Contact for details

Quality Control

Our Eltoprazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.