Description

Sodium (2S,5R,6R)-6-[[1-(3-Bromophenyl)Cyclopentanecarbonyl]Amino]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is a high-purity sodium salt derivative of a complex cephalosporin nucleus, representing a critical advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of next-generation β-lactam antibiotics, offering a precise chemical scaffold for further derivatization. It is essential for pharmaceutical R&D laboratories and API (Active Pharmaceutical Ingredient) manufacturers focused on developing novel anti-infective therapies.

Application

• Key Intermediate in Antibiotic Synthesis: Serves as a crucial building block for the research and production of advanced cephalosporin-class antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new antibacterial agents.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the controlled synthesis of final drug substances targeting resistant bacterial strains.
• Process Chemistry & Scale-Up: Provides a defined starting material for optimizing synthetic routes from laboratory to pilot and commercial scale.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	Sodium (2S,5R,6R)-6-[[1-(3-Bromophenyl)Cyclopentanecarbonyl]Amino]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
CAS No.	143407-70-9
Molecular Formula	C23H26BrN3NaO5S
Molecular Weight	556.43 g/mol
Synonyms	(6R,7R)-7-[[(1-(3-Bromophenyl)cyclopentyl)carbonyl]amino]-3,3-dimethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt; Sodium 7β-[1-(3-Bromophenyl)cyclopentanecarboxamido]-3,3-dimethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; 3-Bromophenyl Cyclopentyl Cephalosporin Sodium Salt; Cephalosporin derivative sodium salt (CAS 143407-70-9); 1-(3-Bromophenyl)cyclopentanecarboxylic acid (6R,7R)-7-amino-3,3-dimethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate sodium salt
EINECS	Contact for details

Quality Control

Our Sodium (2S,5R,6R)-6-[[1-(3-Bromophenyl)Cyclopentanecarbonyl]Amino]-3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.