Description

Sodium (2S,5R,6R)-6-[[1-(4-Chlorophenyl)Cyclopentanecarbonyl]Amino]-3, 3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is a high-purity sodium salt derivative of a penicillanic acid sulfone, representing a key advanced pharmaceutical intermediate. This compound is critical for the synthesis of novel β-lactamase inhibitors, which are essential in combating antibiotic-resistant bacterial infections. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation antibacterial therapies and combination drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potent β-lactamase inhibitors, such as tazobactam analogs.
• Antibiotic Research & Development: Used in preclinical and clinical research to develop new combination therapies that restore the efficacy of penicillin and cephalosporin antibiotics against resistant strains.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up production of finished dosage forms for antibacterial medications.
• Biochemical Research: Acts as a standard or reference compound in studies investigating enzyme inhibition mechanisms and bacterial resistance pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) specializing in complex, high-value pharmaceutical synthesis.

Basic Information

Item	Detail
Product Name	Sodium (2S,5R,6R)-6-[[1-(4-Chlorophenyl)Cyclopentanecarbonyl]Amino]-3, 3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
CAS No.	143407-69-6
Molecular Formula	C22H24ClN2NaO5S
Molecular Weight	486.94 g/mol
Synonyms	Sodium 6β-[[(1-(4-Chlorophenyl)cyclopentyl)carbonyl]amino]penicillanate; Sodium Tazobactam Intermediate; (2S,5R,6R)-6-[(1-(4-Chlorophenyl)cyclopentanecarboxamido)]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt; Tazobactam Acid Sodium Salt; YTR 830H Sodium Salt; CL 298741 Sodium Salt; 6β-[(1-(4-Chlorophenyl)cyclopentanecarboxamido)]penicillanic acid sodium salt
EINECS	Contact for details

Quality Control

Our Sodium (2S,5R,6R)-6-[[1-(4-Chlorophenyl)Cyclopentanecarbonyl]Amino]-3, 3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is manufactured under strict quality systems. Production adheres to cGMP (current Good Manufacturing Practice) guidelines where applicable, ensuring batch-to-batch consistency and traceability. All materials are supported by comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the stringent requirements of the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. The container should be kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.