Description

(S)-(+)-Dbd-Apy CAS NO 143112-49-6 is a high-purity, chiral organic compound belonging to the class of advanced pharmaceutical intermediates and fine chemicals. This enantiomerically pure material is critical for research and development in asymmetric synthesis and the production of active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and process development for novel therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the asymmetric synthesis of chiral drugs, particularly in central nervous system (CNS) and oncology research.
• Ligand Precursor: Used in the preparation of chiral ligands for catalytic asymmetric reactions, including hydrogenation and cross-coupling.
• Analytical Standard: Serves as a reference standard for method development and quality control in chiral HPLC analysis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for API manufacturing under GMP conditions.
• Academic Research: A valuable reagent for studying stereoselective reactions and developing new synthetic methodologies.

Basic Information

Product Name	(S)-(+)-Dbd-Apy
CAS No.	143112-49-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(S)-(+)-2,2'-Dibromo-4,4'-dipyridyl; (S)-(+)-2,2'-Dibromo-4,4'-bipyridine; (S)-2,2'-Dibromo-4,4'-bipyridyl; DBD-APY (S-enantiomer); (S)-DBD-APY; (S)-(+)-DBDAPY; (S)-Enantiomer of 2,2'-Dibromo-4,4'-bipyridine
EINECS	Contact for details

Quality Control

Our (S)-(+)-Dbd-Apy is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and enantiomeric excess. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.