Description

6-Trifluoromethyl-Benzo[B]Thiophene-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block prized for its unique trifluoromethyl-substituted benzothiophene core. This compound is essential for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves lipophilicity and biological activity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Ligand and Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorinated Compound Library: A critical component for constructing diverse screening libraries in drug discovery programs.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke organic synthesis projects at laboratory, pilot, and commercial scales.

Basic Information

Item	Detail
Product Name	6-Trifluoromethyl-Benzo[B]Thiophene-2-Carboxylic Acid
CAS No.	142329-22-4
Molecular Formula	C10H5F3O2S
Molecular Weight	246.21 g/mol
Synonyms	6-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid; 6-(Trifluoromethyl)-1-benzothiophene-2-carboxylic acid; 2-Benzo[b]thiophenecarboxylic acid, 6-(trifluoromethyl)-; 6-Trifluoromethyl-1-benzothiophene-2-carboxylic acid; 6-Trifluoromethylbenzothiophene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Each batch of 6-Trifluoromethyl-Benzo[B]Thiophene-2-Carboxylic Acid is analyzed using advanced techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to support cGMP and ISO standards for research and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.