Description

4-Fluoro-2-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated aromatic building block prized for its unique electronic and steric properties imparted by the fluorine and trifluoromethyl substituents. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure is leveraged to modulate lipophilicity, metabolic stability, and binding affinity. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving performance and durability.
• Polymer Modification: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: A versatile reagent in cross-coupling reactions and for introducing the benzoic acid moiety with fluorine substitution into complex molecules.
• Research & Development: Used in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethyl)Benzoic Acid
CAS No.	141179-72-8
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	2-(Trifluoromethyl)-4-fluorobenzoic Acid; 4-Fluoro-α,α,α-trifluoro-o-toluic Acid; Benzoic acid, 4-fluoro-2-(trifluoromethyl)-; 4-Fluoro-2-trifluoromethylbenzoic Acid; 4-Fluoro-α,α,α-trifluoro-2-methylbenzoic Acid; F-TFMBA (abbrev.)
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Trifluoromethyl)Benzoic Acid is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed and consider storage under an inert atmosphere for long-term preservation to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.