Description

S-(-)-Lisuride is a high-purity, enantiomerically pure ergoline derivative and a potent dopamine receptor agonist. This specific stereoisomer is critical for advanced pharmaceutical research and development, offering precise biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, endocrinology, and the development of treatments for neurological disorders.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for analytical method development, validation, and quality control in drug manufacturing.
• Neuroscience Research: Used as a selective pharmacological tool to study dopamine D2-like receptor signaling pathways and related neurological functions.
• Endocrinology Studies: Applied in research investigating prolactin secretion and the development of potential treatments for hyperprolactinemia.
• Preclinical Development: Acts as a key intermediate or active pharmaceutical ingredient (API) in the early-stage development of novel therapeutic agents.
• Metabolite Identification: Employed in ADME (Absorption, Distribution, Metabolism, and Excretion) studies to identify and characterize metabolic products.

Basic Information

Product Name	S-(-)-Lisuride
CAS No.	140387-89-9
Molecular Formula	C₂₀H₂₆N₄O
Molecular Weight	338.45 g/mol
Synonyms	(8β)-N-[(Diethylamino)ethyl]-6-methylergoline-8-carboxamide; (8β)-N-[2-(Diethylamino)ethyl]-6-methylergoline-8-carboxamide; (-)-Lisuride; S-Lisuride; L-Lisuride; Lisuride S-(-)-enantiomer; Dopergin (enantiomer); LY 201-678 (enantiomer)
EINECS	Contact for details

Quality Control

Our S-(-)-Lisuride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing full specification data is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.