Description

5β-Finasteride is a potent and selective inhibitor of the enzyme 5α-reductase, which is critical in the metabolism of androgens. This compound is of significant interest for its role as a key intermediate in the synthesis of finasteride and related therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of treatments for androgen-dependent conditions, such as benign prostatic hyperplasia (BPH) and androgenetic alopecia.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of the active pharmaceutical ingredient (API) Finasteride.
• Research & Development: Used in biochemical and pharmacological studies to investigate 5α-reductase inhibition and androgen pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Development: Employed in the optimization and scale-up of finasteride manufacturing processes.
• Academic Research: Utilized in university and institutional labs for studies in medicinal chemistry and endocrinology.

Basic Information

Product Name	5β-Finasteride
CAS No.	140375-22-0
Molecular Formula	C₂₃H₃₆N₂O₂
Molecular Weight	372.55 g/mol
Synonyms	5β-Finasteride; 17β-(N-tert-Butylcarbamoyl)-4-aza-5α-androst-1-en-3-one; 4-Aza-5β-androst-1-en-3-one, 17-((1,1-dimethylethyl)amino)carbonyl)-; Finasteride 5β-isomer; Finasteride Impurity; 5β-Dihydrofinasteride
EINECS	Contact for details

Quality Control

Our 5β-Finasteride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent standards for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.