Description

1,8-Naphthyridine-3-Carboxamide, 1,2-Dihydro-1-Butyl-4-Hydroxy-n-(8-Methyl-8-azabicyclo(3.2.1)oct-3-yl)-2-oxo-, endo-, (E)-2-butenedioate (1:1) (Salt) is a high-purity, complex organic salt with significant pharmacological interest. Its value lies in its role as a key intermediate or active pharmaceutical ingredient (API) in advanced research and development, particularly for targeting specific neurological or receptor-based pathways. This compound is essential for pharmaceutical R&D teams, medicinal chemists, and contract manufacturing organizations (CMOs) engaged in the synthesis of novel therapeutic agents. The CAS number for this material is 139094-71-6.

Application

This specialized chemical serves critical functions in advanced scientific and industrial processes:

• Pharmaceutical Intermediate: Primary use as a building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Biochemical Research: Investigation of ligand-receptor interactions and enzyme inhibition studies in academic and industrial laboratories.
• Process Development: Scaling up synthetic routes for preclinical and clinical trial material production under GMP guidelines.

Basic Information

Product Name	1,8-Naphthyridine-3-Carboxamide, 1,2-Dihydro-1-Butyl-4-Hydroxy-n-(8-Methyl-8-azabicyclo(3.2.1)oct-3-yl)-2-oxo-, endo-, (E)-2-butenedioate (1:1) (Salt)
CAS No.	139094-71-6
Molecular Formula	C25H33N3O6 • C4H4O4
Molecular Weight	603.65 g/mol (Salt)
Synonyms	1-Butyl-1,2-dihydro-4-hydroxy-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1,8-naphthyridine-3-carboxamide (E)-2-butenedioate (1:1); Talsaclidine fumarate (1:1); Talsaclidine fumarate salt; WAL 2014 FU; (3-endo)-1-Butyl-1,2-dihydro-4-hydroxy-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1,8-naphthyridine-3-carboxamide (2E)-2-butenedioate (1:1); Talsaclidine (as fumarate)
EINECS	Contact for details

Quality Control

Our production of this compound adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support development under quality systems suitable for cGMP compliance for advanced non-clinical and clinical stage manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccant or inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (anhydrous basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.