Description

Octenoylpenicillin is a semi-synthetic penicillin derivative, a key intermediate in the synthesis of advanced β-lactam antibiotics. Its value lies in providing a versatile chemical scaffold for developing novel antibacterial agents with potentially enhanced activity spectra and stability against β-lactamases. This compound is essential for pharmaceutical R&D teams and manufacturers focused on creating next-generation antibiotic therapies to address evolving microbial resistance.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of novel penicillin and cephalosporin-type antibiotics.
• Antibacterial Research: Serves as a core structure for medicinal chemistry programs aimed at discovering new antibacterial agents.
• Bioconjugation Studies: Used in research exploring the modification of β-lactam antibiotics to alter pharmacokinetic properties.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic & Institutional Research: Utilized in university and institutional labs for studying β-lactam synthesis pathways and resistance mechanisms.

Basic Information

Product Name	Octenoylpenicillin
CAS No.	137593-45-4
Molecular Formula	C23H30N2O6S
Molecular Weight	462.56 g/mol
Synonyms	(2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid oct-2-enoyl ester; 6-APA Octenoyl Ester; (2E)-2-Octenoyl-6-aminopenicillanic acid; Oct-2-enoyl 6-APA; Ampicillin octenoyl ester derivative
EINECS	Contact for details

Quality Control

Our Octenoylpenicillin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.