Description

n-[[5-(Dimethylamino)-1-Naphthalenyl]Sulfonyl]-L-γ-Glutamyl-L-Cysteinylglycine Bimol. (2→2'')-Disulfide is a specialized, high-purity synthetic peptide derivative designed for advanced biochemical and pharmaceutical research. This compound is valued for its role as a key intermediate or reference standard in the development of enzyme inhibitors and diagnostic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in proteomics, drug discovery, and the synthesis of novel therapeutic molecules.

Application

• Biochemical Research: Used as a critical substrate or inhibitor in enzymatic studies, particularly those involving sulfhydryl-reactive enzymes.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of targeted drug candidates, especially in oncology and metabolic disease research.
• Proteomics & Diagnostics: Employed in the development of fluorescent probes and assay kits due to its dansyl (dimethylaminonaphthalene) fluorophore moiety.
• Reference Standard: Provides a high-purity standard for quality control and analytical method validation in GMP and GLP environments.
• Peptide Chemistry: Acts as a building block for constructing more complex peptide conjugates with specific disulfide linkages.

Basic Information

Product Name	n-[[5-(Dimethylamino)-1-Naphthalenyl]Sulfonyl]-L-γ-Glutamyl-L-Cysteinylglycine Bimol. (2→2'')-Disulfide
CAS No.	136346-25-3
Molecular Formula	C34H46N6O12S4
Molecular Weight	851.0 g/mol (approx.)
Synonyms	Dansyl-Glu-Cys-Gly Disulfide; Dns-ECG Disulfide; N-Dansyl-L-glutamyl-L-cysteinylglycine Disulfide; 5-(Dimethylamino)naphthalene-1-sulfonyl-Glu-Cys-Gly Disulfide; L-γ-Glutamyl-L-cysteinylglycine, N-[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-, bimol., (2→2'')-disulfide; Dansyl Glutathione Analogue Disulfide; Fluorescent Peptide Disulfide
EINECS	Contact for details

Quality Control

Our production of this peptide derivative adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized using advanced analytical techniques including HPLC, mass spectrometry (MS), and NMR to confirm identity, purity, and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to ensure traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.