Description

3,4-Difluoro-Benzenebutanoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the benzene ring, which can dramatically alter the physicochemical and metabolic properties of target molecules. This compound is primarily sought by pharmaceutical and agrochemical research & development teams for the creation of novel active ingredients, as well as by fine chemical manufacturers producing specialized intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro motif can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in electronic chemicals for display and lighting technologies.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, potentially improving their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis Research: A valuable reagent in academic and industrial labs for studying fluorination effects and developing new catalytic methodologies.
• Custom Fine Chemical Manufacturing: Supplied for contract synthesis and the production of bespoke, high-value intermediates for various specialty chemical applications.

Basic Information

Product Name	3,4-Difluoro-Benzenebutanoic Acid
CAS No.	136295-00-6
Molecular Formula	C₁₀H₁₀F₂O₂
Molecular Weight	200.18 g/mol
Synonyms	4-(3,4-Difluorophenyl)butanoic Acid; Benzenebutanoic acid, 3,4-difluoro-; 3,4-Difluorobenzene butyric acid; 3,4-Difluorophenylbutyric Acid; γ-(3,4-Difluorophenyl)butyric Acid; 3,4-DFBA; 136295-00-6 (CAS)
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for our fine chemical products. Our 3,4-Difluoro-Benzenebutanoic Acid is manufactured and controlled under current Good Manufacturing Practices (cGMP) where applicable. Identity, purity, and impurity profiles are verified using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.