Description

1,3-Dipropyl-8-(3-Noradamantyl)Xanthine CAS NO 136199-02-5 is a specialized xanthine derivative characterized by its unique noradamantyl substitution. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a high-affinity adenosine receptor antagonist. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutics targeting neurological and cardiovascular pathways. The structural complexity of this molecule offers a valuable scaffold for probing receptor interactions and developing potent, selective agents.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the synthesis of adenosine receptor antagonists.
• Neurological Disorder Studies: Used as a potent tool compound in preclinical research for investigating conditions like Parkinson's disease, ischemia, and sleep disorders due to its receptor binding profile.
• Cardiovascular Research: Employed in studies exploring heart rate regulation, vasodilation, and cardioprotective mechanisms.
• Biochemical Assay Development: Acts as a key ligand in competitive binding assays and high-throughput screening (HTS) to identify new drug candidates.
• Academic & Institutional Research: Provides a sophisticated chemical entity for structure-activity relationship (SAR) studies and medicinal chemistry programs.
• Process Chemistry & Scale-Up: Used in the development and optimization of synthetic routes for GMP-grade production of related therapeutic agents.

Basic Information

Product Name	1,3-Dipropyl-8-(3-Noradamantyl)Xanthine
CAS No.	136199-02-5
Molecular Formula	C21H30N4O2
Molecular Weight	370.49 g/mol
Synonyms	DPNX; 1,3-Dipropyl-8-(3-noradamantyl)xanthine; 8-(3-Noradamantyl)-1,3-dipropylxanthine; Noradamantyl-DPX; Xanthine, 1,3-dipropyl-8-(3-noradamantyl)-; A1 Adenosine Receptor Antagonist DPNX; 8-(3-Noradamantyl)-DPX
EINECS	Contact for details

Quality Control

Our 1,3-Dipropyl-8-(3-Noradamantyl)Xanthine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Assay	97.0% - 102.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.