Description

Xaliproden CAS NO 135354-02-8 is a selective, non-peptide agonist of the 5-HT1A receptor, primarily investigated for its neuroprotective and neurotrophic properties. This compound is of significant interest in pharmaceutical research and development for its potential to modulate serotonergic pathways. It is a critical material for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on developing treatments for neurodegenerative conditions and nerve injury.

Application

• Pharmaceutical Intermediate: Serves as a key active pharmaceutical ingredient (API) or intermediate in the synthesis of neuroprotective drug candidates.
• Neurological Research: Used as a reference standard and investigational tool in preclinical studies targeting amyotrophic lateral sclerosis (ALS), spinal cord injury, and other neurodegenerative diseases.
• Mechanism of Action Studies: Employed in vitro and in vivo to study the activation of 5-HT1A receptors and their downstream effects on neuronal survival and plasticity.
• Drug Discovery & Development: A vital compound for high-throughput screening and lead optimization in central nervous system (CNS) therapeutic programs.
• Biochemical Assays: Utilized in receptor binding assays and functional tests to evaluate compound efficacy and selectivity.

Basic Information

Product Name	Xaliproden
CAS No.	135354-02-8
Molecular Formula	C₁₈H₂₈N₂O₃
Molecular Weight	320.43 g/mol
Synonyms	SR 57746A; SR-57746; SR57746; Xaliprodene; 2-[4-[3-(Dimethylamino)propoxy]phenyl]-5-methyl-1,3-oxazole-4-carboxamide; 4-Carbamoyl-5-methyl-2-[4-[3-(dimethylamino)propoxy]phenyl]oxazole
EINECS	Contact for details

Quality Control

Our Xaliproden is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to meet the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.