Description

3-(2,4-Difluorophenyl)Propionic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role in introducing the difluorophenylpropionic acid moiety, a key structural feature in the development of active pharmaceutical ingredients and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atoms enhance bioactivity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Polymer Science: Employed as a monomer or modifier to create specialty polymers with unique thermal and chemical resistance properties.
• Organic Synthesis Reagent: Utilized in coupling reactions, such as Suzuki or Heck reactions, to construct complex fluorinated aromatic systems.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring structure-activity relationships in medicinal chemistry.

Basic Information

Product Name	3-(2,4-Difluorophenyl)Propionic Acid
CAS No.	134672-70-1
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2,4-Difluorohydrocinnamic Acid; 3-(2,4-Difluorophenyl)propanoic Acid; (2,4-Difluorophenyl)propionic Acid; β-(2,4-Difluorophenyl)propionic Acid; 2,4-DFPA; NSC 339243; 3-(2,4-Difluorophenyl)propionsäure (German); Acide 3-(2,4-difluorophényl)propanoïque (French)
EINECS	Contact for details

Quality Control

Our 3-(2,4-Difluorophenyl)Propionic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.