Description

Benzoic Acid, 2-(Aminocarbonyl)-3,4,5,6-Tetrafluoro- is a highly fluorinated benzoic acid derivative, distinguished by its unique tetrafluoro substitution pattern and amide functionality. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex molecules. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Building block for novel herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Used in the development of fluorinated components for advanced display technologies.
• Polymer Modification: Incorporation into polymers to impart specific chemical resistance, thermal stability, or surface properties.
• Organic Synthesis Reagent: Serves as a fluorinated synthon in cross-coupling reactions and amide bond formation for complex molecule assembly.
• Research & Development: Essential compound for academic and industrial research exploring structure-activity relationships (SAR) in fluorinated aromatic systems.

Basic Information

Product Name	Benzoic Acid, 2-(Aminocarbonyl)-3,4,5,6-Tetrafluoro-
CAS No.	133492-64-5
Molecular Formula	C8H3F4NO3
Molecular Weight	237.11 g/mol
Synonyms	2-Carbamoyl-3,4,5,6-tetrafluorobenzoic Acid; 3,4,5,6-Tetrafluoro-2-(aminocarbonyl)benzoic Acid; Tetrafluorophthalamic Acid; 2-Aminocarbonyl-3,4,5,6-tetrafluorobenzoic Acid; Perfluoroisophthalamic Acid; 3,4,5,6-Tetrafluorophthalamic Acid; AI3-71042; BRN 8730196
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 2-(Aminocarbonyl)-3,4,5,6-Tetrafluoro- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical processes. All materials undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support development and commercial projects requiring compliance with cGMP and ISO 9001 quality management standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.