Description

Duramycin C is a specialized lantibiotic peptide known for its potent biological activity. This compound is valued for its ability to interact with phosphatidylethanolamine in cell membranes, making it a crucial tool in biochemical and pharmacological research. It is primarily sought by researchers and developers in the life sciences, pharmaceutical, and biotechnology sectors for applications in membrane studies, antimicrobial research, and as a potential therapeutic agent scaffold.

Application

• Biochemical Research: Used as a specific probe for studying phosphatidylethanolamine (PE) distribution and function in biological membranes.
• Antimicrobial Studies: Investigated for its mechanism of action against Gram-positive bacteria and its potential in developing new antibiotic leads.
• Cell Biology: Employed in assays to investigate membrane permeability, pore formation, and ion channel activity.
• Pharmaceutical Development: Serves as a reference standard or starting material in the research and development of novel peptide-based therapeutics.
• Diagnostic Reagent Formulation: Potential use in developing sensitive assays for detecting specific membrane components or cellular states.

Basic Information

Item	Detail
Product Name	Duramycin C
CAS No.	132268-38-3
Molecular Formula	C107H144N24O31S4
Molecular Weight	2342.7 g/mol
Synonyms	Duramycin C; Lantibiotic Duramycin C; Antibiotic M-26; Cinnamycin-related peptide; Peptide antibiotic M-26; Duramycin C (Streptomyces cinnamoneus); [Val1, Lys2, Ala6]Cinnamycin; (3S)-3-Amino-6-{[(2S)-1-{[(2S,5R,8S,11S,14S,17S,20S,23S,26S,29S,32S,35S,38S)-11-[(2S)-butan-2-yl]-14-[(2R)-1-hydroxybutan-2-yl]-17-[(1S)-1-hydroxyethyl]-20-[(1R)-1-hydroxyethyl]-23-(4-hydroxybenzyl)-26-[(1S)-1-hydroxyethyl]-29-[(1R)-1-hydroxyethyl]-32-[(1S)-1-hydroxyethyl]-35-(hydroxymethyl)-5,8,38-tris(2-methylpropyl)-2,13,16,19,22,25,28,31,34-nonaoxo-1-oxa-4,7,10,15,18,21,24,27,30,33,36-undecaazatricyclo[36.3.0.04,9]hentetracontan-3-yl]amino}-4-methyl-1-oxopentan-2-yl]amino}-6-oxohexyl]carbamic acid
EINECS	Contact for details

Quality Control

Our Duramycin C is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and potency is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Potency (Microbiological Assay)	Contact for details
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.