Description

o-β-Ribosyl(1''-2')-Guanosine-5''-Phosphate is a specialized nucleotide derivative, a key building block in advanced biochemical research and development. This compound is valued for its role in studying RNA structure, enzyme mechanisms, and nucleotide metabolism. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from drug discovery to the synthesis of novel nucleic acid analogs.

Application

• Biochemical Research: A critical intermediate for investigating RNA splicing mechanisms, ribozyme activity, and nucleotide-protein interactions.
• Pharmaceutical Development: Used in the synthesis and screening of novel antiviral and anticancer nucleoside analogs.
• Enzymology Studies: Serves as a substrate or inhibitor for studying the kinetics and specificity of nucleotidyltransferases and phosphorylases.
• Diagnostic Reagent Synthesis: A precursor for manufacturing labeled probes and other reagents used in molecular diagnostics.
• Nucleic Acid Chemistry: Employed in the chemical synthesis of modified oligonucleotides with unique structural or functional properties.

Basic Information

Product Name	o-β-Ribosyl(1''-2')-Guanosine-5''-Phosphate
CAS No.	131293-20-4
Molecular Formula	C15H22N5O13P2
Molecular Weight	566.31 g/mol
Synonyms	2'-O-β-Ribosylguanosine 5''-phosphate; Guanosine 5''-phosphate, 2'-O-β-D-ribofuranosyl-; 2'-O-(β-D-Ribofuranosyl)guanosine 5''-phosphate; o-β-Ribosyl(1''-2')guanosine 5''-phosphate; 2'-O-Ribosylguanosine 5''-phosphate; 2'-O-(β-Ribosyl)guanosine 5''-phosphate; Gp(2'-5')G analog; Nucleotide disaccharide derivative
EINECS	Contact for details

Quality Control

Our o-β-Ribosyl(1''-2')-Guanosine-5''-Phosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.