Description

Sulforhodamine Q 5-Acid Fluoride is a reactive dye intermediate, specifically an activated ester derivative, designed for efficient bioconjugation. This compound is valued for its ability to form stable amide bonds with primary amines under mild conditions, enabling the labeling of proteins, peptides, and other biomolecules. It is primarily utilized by researchers and manufacturers in the fields of biotechnology, diagnostics, and pharmaceutical development for creating fluorescent probes and assay reagents.

Application

• Fluorescent Probe Synthesis: Key intermediate for preparing sulforhodamine Q-labeled probes for fluorescence microscopy and imaging.
• Bioconjugation & Labeling: Used to covalently attach fluorescent tags to antibodies, proteins, and oligonucleotides for diagnostic assays (e.g., ELISA, flow cytometry).
• Biomarker Detection Reagents: Manufacture of high-sensitivity detection kits for clinical and research applications.
• Chemical Biology Research: Tool for studying protein-protein interactions, cellular localization, and molecular trafficking.
• Polymer & Material Science: Functionalization of surfaces and nanomaterials with fluorescent markers for sensor development.

Basic Information

Product Name	Sulforhodamine Q 5-Acid Fluoride
CAS No.	130689-24-6
Molecular Formula	C33H31F2N2O7S2
Molecular Weight	677.74 g/mol
Synonyms	Sulforhodamine Q Acid Fluoride; QSY 7 Acid Fluoride; Sulforhodamine 101 Acid Fluoride derivative; 5-Carboxysulforhodamine 101 Acid Fluoride; SR Q 5-Acid Fluoride; Texas Red-type Acid Fluoride; Xanthylium, 9-[2-(carboxycarbonyl)phenyl]-3,6-bis(diethylamino)-, inner salt, 2,7-difluoride; Reactive red dye intermediate.
EINECS	Contact for details

Quality Control

Our Sulforhodamine Q 5-Acid Fluoride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive bioconjugation applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain reactivity. Keep container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.