Description

5-Chloro-2,4-Difluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen substituents, which enable precise molecular modifications for creating complex, high-performance compounds. This intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the difluoro and chloro groups contribute to biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique thermal, chemical, or surface properties.
• Organic Electronic Materials: Used in research for developing novel organic semiconductors and electron-transport materials.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies and novel compound libraries.

Basic Information

Product Name	5-Chloro-2,4-Difluorobenzoic Acid
CAS No.	130025-33-1
Molecular Formula	C7H3ClF2O2
Molecular Weight	192.55 g/mol
Synonyms	2,4-Difluoro-5-chlorobenzoic Acid; Benzoic acid, 5-chloro-2,4-difluoro-; 5-Chloro-2,4-difluorobenzoic acid; 130025-33-1
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2,4-Difluorobenzoic Acid is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity data, identity confirmation (IR, NMR), and impurity profiles. Our quality commitment ensures reliable consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.