Description

Benzoyl Fluoride, 2,4,6-Trifluoro- (9Ci) CAS NO 129825-18-9 is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic introduction of fluorine atoms and a reactive benzoyl fluoride moiety, enabling precise molecular modifications to enhance the properties of target compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients with improved metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where fluorine incorporation improves efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated compounds used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated benzoyl groups into polymer chains, enhancing material properties like chemical resistance and thermal stability.
• Complex Ligand Synthesis: Facilitates the creation of fluorinated ligands for catalysis and metal-organic frameworks (MOFs).
• Positron Emission Tomography (PET) Tracer Development: Potential precursor for synthesizing fluorine-18 labeled radiopharmaceuticals for medical imaging.

Basic Information

Product Name	Benzoyl Fluoride, 2,4,6-Trifluoro- (9Ci)
CAS No.	129825-18-9
Molecular Formula	C7H2F4O
Molecular Weight	178.09 g/mol
Synonyms	2,4,6-Trifluorobenzoyl Fluoride; 2,4,6-Trifluorobenzoic Acid Fluoride; α,2,4,6-Tetrafluorotoluene; Perfluorotoluene (incorrect but common alias); Benzoyl fluoride, α,2,4,6-tetrafluoro-; 2,4,6-Trifluorobenzcarbonyl fluoride
EINECS	Contact for details

Quality Control

Our Benzoyl Fluoride, 2,4,6-Trifluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and GC-MS for identity confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by HPLC)	≥ 98.0%
Assay (by GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.