Description

2-Hydroxy-5-(Trifluoromethylthio)Benzoic Acid is a high-value fluorinated aromatic building block characterized by its unique combination of a carboxylic acid, a phenolic hydroxyl group, and a trifluoromethylthio substituent. This structure makes it a critical intermediate for synthesizing advanced agrochemicals and pharmaceuticals, where it imparts desirable properties like enhanced metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylthio group.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas requiring fluorinated motifs for improved pharmacokinetics.
• Liquid Crystal & Electronic Materials: Serves as a precursor for advanced functional materials used in display technologies and organic electronics.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, altering surface properties and chemical resistance.
• Organic Synthesis Reagent: Acts as a versatile starting material or coupling partner in cross-coupling reactions and other synthetic transformations.
• Research & Development: Essential for academic and industrial research exploring new chemical entities with fluorinated architectures.

Basic Information

Item	Detail
Product Name	2-Hydroxy-5-(Trifluoromethylthio)Benzoic Acid
CAS No.	129644-58-2
Molecular Formula	C8H5F3O3S
Molecular Weight	238.18 g/mol
Synonyms	5-(Trifluoromethylthio)salicylic acid; 2-Hydroxy-5-[(trifluoromethyl)sulfanyl]benzoic acid; Benzoic acid, 2-hydroxy-5-[(trifluoromethyl)thio]-; Salicylic acid, 5-(trifluoromethylthio)-; 5-(Trifluoromethylthio)-2-hydroxybenzoic acid; 2-Hydroxy-5-(trifluoromethylmercapto)benzoic acid; 5-(Trifluoromethylsulfanyl)salicylic acid
EINECS	Contact for details

Quality Control

Our production of 2-Hydroxy-5-(Trifluoromethylthio)Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide Certificates of Analysis (COA) with each shipment, detailing all specification results to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.