Description

2-Hydroxy-5-(Trifluoromethoxy)Benzoic Acid is a high-value trifluoromethoxy-substituted benzoic acid derivative, serving as a critical building block in advanced chemical synthesis. Its unique molecular structure, combining a carboxylic acid group with a hydroxy and a trifluoromethoxy substituent, makes it indispensable for creating compounds with enhanced biological activity and stability. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

This versatile chemical intermediate finds application across several high-tech industries:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethoxy group can improve lipophilicity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for advanced liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Complex Ligand Synthesis: Useful in coordination chemistry for creating specialized ligands in catalytic systems.
• Advanced Polymer Research: Acts as a monomer or modifier in the synthesis of high-performance, specialty polymers.

Basic Information

Product Name	2-Hydroxy-5-(Trifluoromethoxy)Benzoic Acid
CAS No.	129644-57-1
Molecular Formula	C8H5F3O4
Molecular Weight	222.12 g/mol
Synonyms	5-(Trifluoromethoxy)salicylic acid; 2-Hydroxy-5-(trifluoromethoxy)benzoic acid; Salicylic acid, 5-(trifluoromethoxy)-; Benzoic acid, 2-hydroxy-5-(trifluoromethoxy)-; 5-Trifluoromethoxysalicylic acid; 2-Hydroxy-5-trifluoromethoxybenzoic acid; 5-(Trifluoromethoxy)-2-hydroxybenzoic acid
EINECS	Contact for details

Quality Control

Our production of 2-Hydroxy-5-(Trifluoromethoxy)Benzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting customer specifications. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our quality system is designed to support applications requiring high-purity intermediates under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture. Due to its chemical nature, store away from strong bases and fluorides. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.