Description

7-Benzylidenenaltrexonemaleate is a specialized pharmaceutical intermediate and research chemical with the CAS registry number 129468-28-6. This compound is of significant interest for its role in the development and synthesis of novel opioid receptor modulators and related therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in advanced medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of opioid receptor antagonists and related pharmacologically active compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents targeting neurological pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in vitro studies to investigate ligand-receptor interactions and signal transduction mechanisms.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, high-value molecular architectures.

Basic Information

Item	Details
Product Name	7-Benzylidenenaltrexonemaleate
CAS No.	129468-28-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	7-Benzylidenenaltrexone maleate; 7-Benzylidene-17-(cyclopropylmethyl)-4,5α-epoxy-6-oxomorphinan-3,14-diol maleate; Naltrexone benzylidene derivative maleate; 7-Benzylidene naltrexone maleate salt; BNTX maleate (commonly used abbreviation); 7-Benzylidenenaltrexone hydrogen maleate
EINECS	Contact for details

Quality Control

Our 7-Benzylidenenaltrexonemaleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.