Description

5-n-Acetyl-9-(4-Azidosalicoylamido)-2-Deoxy-2,3-Didehydroneuraminic Acid is a specialized, chemically modified neuraminic acid derivative featuring a photoreactive azido group. This compound is engineered as a critical biochemical tool for advanced research and development, enabling precise covalent labeling and cross-linking studies. It is primarily utilized by scientists and manufacturers in the fields of glycobiology, pharmaceutical development, and diagnostic reagent production, where its unique functionalization allows for the study and manipulation of sialic acid-dependent biological processes.

Application

• Glycobiology Research: A key reagent for studying sialic acid (neuraminic acid) metabolism, function, and its role in cell signaling and pathogen recognition.
• Photoaffinity Labeling: The azido group enables UV-induced cross-linking to probe protein-carbohydrate interactions and map binding sites.
• Bioconjugation & Probe Synthesis: Serves as a building block for creating fluorescent, biotinylated, or other tagged probes for imaging and detection assays.
• Enzyme Substrate & Inhibitor Studies: Used to investigate the activity and mechanism of sialidases (neuraminidases) and sialyltransferases.
• Antiviral & Vaccine Research: Supports the development of novel inhibitors targeting viral neuraminidases, relevant to influenza and other viruses.
• Diagnostic Development: Employed in the synthesis of components for diagnostic kits that detect sialic acid-related biomarkers.

Basic Information

Product Name	5-n-Acetyl-9-(4-Azidosalicoylamido)-2-Deoxy-2,3-Didehydroneuraminic Acid
CAS No.	129178-63-8
Molecular Formula	C18H19N5O9
Molecular Weight	449.37 g/mol
Synonyms	4-Azidosalicoylamido-Neu5Ac2en; 9-(4-Azidosalicoylamido)-2-deoxy-2,3-didehydro-N-acetylneuraminic Acid; 5-Acetamido-9-(4-azidosalicoylamido)-2,6-anhydro-3,5-dideoxy-D-glycero-D-galacto-non-2-enonic Acid; Neu5Ac2en-9-azidosalicylamide; Azido-Sia2en Derivative; Sialic Acid Azido Probe; Photoactivatable Neuraminic Acid Analog
EINECS	Contact for details

Quality Control

Our production of this high-purity biochemical adheres to stringent quality protocols. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry to confirm identity, purity, and functional integrity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to ensure traceability and support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.