Description

1-(Myristoyl)-2-(7,7-Difluoromyristoyl)Glycero-3-Phosphocholine CAS NO 128022-95-7 is a high-purity, synthetic phospholipid featuring a unique difluorinated fatty acyl chain. This specialized structure is critical for modulating the biophysical properties of lipid membranes, particularly their stability and permeability. It is an essential research-grade biochemical for scientists in lipidomics, membrane biophysics, and advanced drug delivery system development, especially for creating fluorinated liposomes and lipid nanoparticles (LNPs).

Application

• Lipid Nanoparticle (LNP) Formulation: A key component for constructing stable, next-generation LNPs used in mRNA and siRNA delivery systems.
• Membrane Biophysics Research: Used to study the effects of fluorinated lipids on membrane fluidity, phase behavior, and permeability in model bilayer systems.
• Synthetic Liposome Production: Incorporated into liposomal formulations to enhance serum stability and control drug release profiles.
• Biomimetic Membrane Engineering: Serves as a building block for creating advanced artificial cell membranes and membrane protein research platforms.
• Diagnostic Reagent Development: Utilized in the synthesis of specialized reagents for fluorescence-based assays and imaging techniques.
• Pharmaceutical R&D: A vital raw material for preclinical research into novel targeted therapeutics and vaccine adjuvants.

Basic Information

Item	Details
Product Name	1-(Myristoyl)-2-(7,7-Difluoromyristoyl)Glycero-3-Phosphocholine
CAS No.	128022-95-7
Molecular Formula	C₃₉H₇₆F₂NO₈P
Molecular Weight	756.00 g/mol
Synonyms	14:0-14:0(7,7-diF) PC; 1-Myristoyl-2-(7,7-difluoromyristoyl)-sn-glycero-3-phosphocholine; Difluorinated Phosphatidylcholine; PC(14:0/14:0(7,7-diF)); 1,2-Dimyristoyl-7,7-difluorophosphatidylcholine; Fluorolipid PC; (7,7-Difluoromyristoyl) Phosphocholine Derivative; Lyso PC Difluoro Analog
EINECS	Contact for details

Quality Control

Every batch of our 1-(Myristoyl)-2-(7,7-Difluoromyristoyl)Glycero-3-Phosphocholine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency suitable for sensitive research applications. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic and moisture-sensitive; allow the vial to equilibrate to room temperature in a desiccator before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.