Description

3'-Azido-3'-Deoxythymidine 5'-(Tetrahydrogen Triphosphate) Compd. With N,n-Diethylethanamine (1:3) is a chemically modified nucleoside triphosphate analog, specifically the triphosphate form of Azidothymidine (AZT). This compound is a critical biochemical reagent for studying viral replication mechanisms and nucleotide metabolism. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery and molecular biology research.

Application

• Biochemical Research: As a substrate analog for DNA polymerases, particularly reverse transcriptase, in enzymatic studies and inhibition assays.
• Antiviral Mechanism Studies: Investigation of the chain termination mechanism of nucleoside reverse transcriptase inhibitors (NRTIs) like AZT.
• Probe Development: Potential use in developing probes for labeling or cross-linking experiments due to the reactive azido group.
• Nucleotide Metabolism Research: Studying the incorporation and effects of modified nucleotides in cellular processes.
• Pharmaceutical R&D: Serving as a key intermediate or reference standard in the development and quality control of antiviral therapeutics.

Basic Information

Product Name	3'-Azido-3'-Deoxythymidine 5'-(Tetrahydrogen Triphosphate) Compd. With N,n-Diethylethanamine (1:3)
CAS No.	127753-52-0
Molecular Formula	C10H16N5O13P3 • 3(C6H15N)
Molecular Weight	Contact for details
Synonyms	AZT Triphosphate Triethylamine Salt; 3'-Azido-3'-deoxythymidine 5'-triphosphate; Azidothymidine Triphosphate; AZTTP; 3'-Azido-2',3'-dideoxythymidine 5'-triphosphate; 2',3'-Dideoxy-3'-azidothymidine 5'-triphosphate; d4TTP analog (AZT); Nucleoside triphosphate analog
EINECS	Contact for details

Quality Control

Our 3'-Azido-3'-Deoxythymidine 5'-(Tetrahydrogen Triphosphate) Compd. With N,n-Diethylethanamine (1:3) is produced under strict quality management protocols. Each batch is characterized and tested to ensure high purity and consistency suitable for sensitive biochemical applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (NMR, MS), and other critical parameters is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the product to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.