Description

6-(3-Phenylpropyl)Oximino Naltrexone is a specialized pharmaceutical intermediate and research chemical. This compound is significant for its role in the development and synthesis of novel opioid receptor antagonists and related therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in neuropharmacology and medicinal chemistry research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced opioid receptor modulators and naltrexone derivatives.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new treatments for addiction and pain management.
• Biochemical Research: Serves as a tool compound for investigating opioid receptor binding and signal transduction pathways.
• Reference Standard: Employed as a high-purity analytical standard in quality control and method development for related APIs.
• Preclinical Development: Utilized in the early-stage development of novel therapeutic candidates targeting the central nervous system.

Basic Information

Product Name	6-(3-Phenylpropyl)Oximino Naltrexone
CAS No.	127227-11-6
Molecular Formula	C29H34N2O4
Molecular Weight	474.60 g/mol
Synonyms	6-(3-Phenylpropyl)oximinonaltrexone; 6β-(3-Phenylpropyl)oximino-17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan; 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-6β-[(3-phenylpropyl)oximino]morphinan; Naltrexone 6-(3-Phenylpropyl)oxime; 6β-(3-Phenylpropyl)oximino Naltrexone; 6-(3-Phenylpropyl)oximino-17-(cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan
EINECS	Contact for details

Quality Control

Our 6-(3-Phenylpropyl)Oximino Naltrexone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.