Description

2-Methoxyapomorphine is a synthetic derivative of the dopamine agonist apomorphine, characterized by the addition of a methoxy group to its core structure. This modification is of significant interest in pharmaceutical research for its potential to influence receptor binding affinity and selectivity. It serves as a critical pharmaceutical intermediate and reference standard for researchers and developers in the life sciences sector, particularly those focused on central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel dopaminergic compounds for research and development.
• Neurological Research: Used as a reference standard and active compound in preclinical studies targeting dopamine receptors.
• Chemical Synthesis: Acts as a versatile precursor for the development of new chemical entities with potential therapeutic applications.
• Analytical Standard: Employed in analytical laboratories for method development, validation, and quality control (HPLC, LC-MS).
• Biochemical Assays: Utilized in in vitro assays to study receptor-ligand interactions and signal transduction pathways.
• Academic Research: Supports fundamental research in medicinal chemistry, neuropharmacology, and drug discovery programs.

Basic Information

Product Name	2-Methoxyapomorphine
CAS No.	126874-79-1
Molecular Formula	C18H19NO3
Molecular Weight	297.35 g/mol
Synonyms	2-Methoxyapomorphine; 2-Methoxy-apomorphine; 2-Methoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; Apomorphine, 2-methoxy-; (6aR)-2-Methoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; (R)-2-Methoxyapomorphine
EINECS	Contact for details

Quality Control

Our 2-Methoxyapomorphine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.